Improving bioactivity and strength of PEEK composite polymer for bone application

Poly-Ether-Ketone (PEEK) is a bioactive material capable of replacing traditional metal and ceramic components in biomedical applications but still lacks some strength biological propertices compared with natural bone. In this research, calcium hydroxyapatite (cHAp) reduced Graphene oxide (rGO) were combined PEEK, different lattice porose structures produced to improve interfaces biocompatibility mimick the The FDM method was used obtain rGOcHAP composites coated, Finite Element Analysis (FEA) simulate conditions varying ratio. new PEEK/rGO/cHAP composite characterisation obtained by SEM analysis mechanical via compressive tensile test. highest proportion rGO 5% shows more strength. Young modulus bulk PEEK increase exponentially from 3.85Gpa 54.965% 5 wt% addition rGO. Also, PEEK/rGo/cHAp induces cell formation after several days immersion body fluids simulated Dulbecco's Modified Eagle Medium (DMEM) Nutrient Agar Solution (NAS) determine their bioactivity. vivo experiments showed that aggregation activity around higher than NAS growth bioactivity DMEM.